Jamels was born in Pettai, Tamil Nadu, India. After being ordained as a priest in 1989, he worked as a secretary to his bishop and was associate Pastor at the St. Francis Xavier Cathedral. He also served as Lecturer for three years at St. Paul’s Major Seminary. In 2003, along with four other Indian priests, he started EXCELL (now LIFT) in India to cultivate leadership excellence among the poor, gifted children.
Jamels earned an Executive MBA at Kellogg School of Management June, 2007.